Synthesis of 1,4‐Dicarbonyl Compounds via Visible‐Light‐Induced Decarboxylative Radical Cascade Reactions.

The inside cover picture illustrates the introduction of a catalyst-free three-component coupling reaction for synthesis 1,4-dicarbonyl compounds. This innovative process employs light-activated electron donor-acceptor complexes to initiate single-electron reduction via carboxylic acid derivatives, triphenylphosphine, and sodium iodide. Subsequently, decarboxylation fragmentation gives rise nucleophilic alkyl radicals, enabling sequential radical with both electron-deficient electron-rich olefins. approach showcases extensive substrate compatibility, offering well-defined pathway valuable compounds highlighting its versatility various transformations modification natural products. Details can be found in Communication by Hongze Liao co-workers (Z. Su, J. Zhang, H.-W. Lin, H. Liao, Adv. Synth. Catal. 2023, 365, XXXX–XXXX; DOI: 10.1002/adsc.202300645)